Why does KOH (potassium hydroxide) absorb CO2. 7A respiratory frequency of 10 breaths/min was used, and a tidal volume of 490 ml, aiming at an end-tidal carbon dioxide partial pressure of 40 mmHg, measured at the Ultima gas analyzer. Only by eliminating both KOH and NaOH from the absorbent is no compound A produced; thus, we can comply with the message about “putting the brakes on anesthetic breakdown” of a recent editorial on that subject. The results for compound Ainspwith the different carbon dioxide absorbents are shown in figure 1. Asked By Michelle Littel. Standards of compound A in the gas phase were prepared starting from liquid volumetric dilutions of stock solutions of compound A and sevoflurane in ethyl acetate. A significant correlation (P < 0.05) was found between compound Ainspvalues and canister T°outin the Sofnolime (r = 0.49) group only. To enter enough analyte mass into the analytic system and thus reach the intended sensitivity, cryofocusing on Tenax®(Alltech Associates, Deerfield, IL) sorbent (liquid nitrogen coolant, −80°C), placed in the injector liner, followed by flash desorption (250°C), was applied, and the compounds transferred onto the capillary column. 4There is increasing evidence that the presence of strong bases, such as NaOH and KOH, as initiators in the carbon dioxide binding process may be the important factor in the dehalogenation of sevoflurane to compound A. Stabernack et al. What is the birthday of carmelita divinagracia? A less pronounced increase, but with a similar time curve, was also seen with the KOH-free Sodasorb (group difference, P < 0.05 with all remaining other groups), when compared with the NaOH-containing as well as KOH-containing Sodasorb. A difference in absorption of sevoflurane in the used absorbents (standard hydrated, not dry in our setup) might be another possibility because Stabernack et al. ... Why does KOH (potassium hydroxide) absorb CO2? These facts suggest the importance not only of the presence or absence of KOH or NaOH, or both, in the carbon dioxide absorbent, but also, the exact concentration. After baseline analysis, liquid sevoflurane was injected into the circuit by syringe pump to obtain 2.1% end-tidal concentration for 240 min. The canister temperatures were almost the same for all absorbents examined, with T°outhigher than T°in; the only exception was with lithium hydroxide, which generated much higher temperatures (P < 0.05), with T°induring the first 120 min higher than T°out. Before analysis, 0.5 μl of a liquid solution containing the internal standard in ethyl acetate was added to each vial. One was sited in the lower inflow, measuring inflow temperature (T°in), and one in the upper outflow, measuring outflow temperature (T°out). The authors thank Etienne Soens (Technician, Department of Anesthesia, Ghent University Hospital, Gent, Belgium). Various fresh carbon dioxide absorbents were used: Sodasorb (n = 6), Sofnolime (n = 6), and potassium hydroxide (KOH)-free Sodasorb (n = 7), Amsorb (n = 7), and lithium hydroxide (n = 7). Why does KOH (potassium hydroxide) absorb CO2? 1However, different carbon dioxide absorbents vary enormously in their capacity to produce compound A. Table 1. We need pressure to dissolve CO2. Insufficient data exist on the production of compound A during closed-system sevoflurane administration with newer carbon dioxide absorbents. 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