Ultimately, those taking the statin (rosuvastatin in this case) had lower levels of bad LDL cholesterol and hsCRP as well as fewer heart attacks, strokes, and death during the study’s one year time period. In this study, 7% of the participants who were non-obese before they took statins or blood pressure drugs became obese by the end of the study. Statin drugs are anti-inflammatories. And 2 other important rules. Neurological side effects The print version of the Daily Mirror has incorrectly reported the results of new research about lifestyle changes associated with taking statins or blood pressure drugs. The reason this supplement can work is that its the active ingredient is a statin–lovastatin! Around 7-8 million adults in the UK are on statins - they’re one of the UK’s most commonly prescribed drugs. Study Shows Weight Gain, More Calories Consumed - Medscape - Apr 24, … It promotes hate, damages people’s health, and hurts democracy. One of the largest clinical studies that validated these extra benefits of statins was title Justification for the Use of Statins in Primary Prevention: An Intervention Trial Evaluating Rosuvastatin, aka the JUPITER trials. I would estimate that only 1-2 out of every 10 of my patients taking a statin actually complain of any soreness. A 2012 study sought to answer this exact question and found that two statins (simvastatin and pravastatin) caused changes in energy, most notably in women. It also raised the good HDL cholesterol by 10% and lowered triglycerides by 28%. The Daily Mirror, 6 February 2020. Such products are not regulated by the FDA and so they are not bound by the same manufacturing and safety standards. ... By Max Stephens 25 Nov 2020, 3:12pm. Supplementing CoQ10 seems to help improve medication adherence for some. Privacy, terms and conditions. However, side effects may be a concern, especially if you have effects that are painful or bothersome. Results were consistent across all major studies: statins reduced LDL cholesterol (often called bad cholesterol) up to 35%. This was also the era of antibiotics. A study found that the risk of becoming obese increased by 82% among participants who were prescribed statins or blood pressure drugs, not that 82% risked becoming obese. The PA Doctor Clinical Medicine. Most of my patients are low in Vitamin D which I believe has to do with our northern latitude. On the other hand, the ability of statins to prevent hardening and narrowing of the arteries can actually help prevent dementia given that vascular disease is a leading cause of the same. Thanks to Bytemark for donating our web hosting, and Alamy for providing stock photos. Some patients prefer to take a more natural approach and choose to treat their high cholesterol with red yeast rice. This is called a pleiotropic effect, i.e. This study does not prove that these drugs caused the weight gain. Simvastatin and pravastatin hold the distinguished designation of being the most tolerable statins with the fewest side effects. One of the medications I prescribe most often are the statins that lower cholesterol and risk of heart attack and stroke. We’ve seen people claiming to be health professionals, family members, and even the government – offering dangerous tips like drinking warm water or gargling to prevent infection. Today, you have the opportunity to help save lives. 6975984) limited by guarantee and registered in England and Wales. They will very likely extend your life. But available medications in the 1950s and 60s were not very effective and not well tolerated–the Framingham Heart Study (among others) had only recently cemented the link between the two. Alexander Fleming discovered penicillin a few decades prior and pharmaceutical companies were actively searching for new antibiotics. This may be statistically significant but unlikely clinically significant. Research, published in the Journal of the American Heart Association, reports on the benefits of heart healthy lifestyle choices alongside statins or blood pressure drugs.. Prof Tim Chico, Professor of Cardiovascular Medicine and Honorary Consultant Cardiologist, University of Sheffield, said: A British study evaluated 20,000 individuals, this time considered to be high-risk meaning that they had to have at least one of the following criteria: Not only did taking simvastatin, in this case, lower the number of heart attacks and stroke but it saved lives. Hydrophilic statins such as rosuvastatin, fluvastatin, and pravastatin are. Some people experience a slight increase in blood sugar, which for healthy individuals is often irrelevant. There are some reports of a mild, transient decrease in cognition when starting a statin. a beneficial effect outside of what was expected. One analysis has shown that people who take statin drugs tend to increase their fat intake in addition to consuming more calories overall. As we’ve already noted, that number of participants who became obese over the course of the study was only 7% of the total. But the short term effects of cortisol are quite interesting. Read more about Clinical Medicine on The PA Doctor: Your email address will not be published. There are several “tricks” I have to improve statin tolerability, though evidence indicates that they may not work for everyone. The 1991 EXCEL study found one case of myopathy among almost 5,000 patients taking up to 40 mg of lovastatin over 3 years. We need your help to protect us all from false and harmful information. I’ve never had anyone complain of weakness or fatigue. Coronary events were defined as a heart attack, severe chest pain (angina), or sudden cardiac death. So are statins really worth taking? In addition, as acknowledged in the paper, the findings cannot be applied to the wider population in Finland where the study was conducted (or the UK). If you have read about the potential side effects of statins, you may be more likely to blame your symptoms on the medication, whether or not they're truly caused by the drug. A negative effect on cognition and dementia has not been proven. 1158683) and a non-profit company (no. Muscle pain and damage. “A study of 40,000 patients found of those prescribed [statins or blood pressure pills], 82% were more likely to become obese or increase their body mass index in the next four years”. A study of over 6,000 men and women in Texas who had elevated cholesterol but no history of heart disease found that coronary events were reduced by almost 40%. Patients should exercise caution when purchasing supplements online as they could contain variable amounts of lovastatin. Merck, the manufacturer of the first commercialized statin, recommended that lovastatin, or Mevacor, only be used as an adjunct to a healthful diet and when the response to diet alone was inadequate to reduce risk. 82% of study participants who were prescribed statins or blood pressure pills were more likely to gain weight. The print version of the Daily Mirror has incorrectly reported the results of new research about lifestyle changes associated with taking statins or blood pressure drugs. Cite this: Off the Lifestyle Hook with Statins? The analysis showed an average reduction of 0.25 points with simvastatin and 0.17 points with pravastatin. These, and other unmeasured factors, may explain why participants who were prescribed drugs were more likely to gain weight. Of note, the US Food and Drug Administration (FDA) actually doesn’t allow lovastatin-containing red yeast rice products on the US market. Full Fact is a registered charity (no. What are statin side effects? Statins increase weight and blood sugar levels and raise the risk of diabetes, a study has found, but experts maintain that the benefits of the drug "greatly outweigh" the risks. More importantly, was the fact that the medications reduced heart attacks by up to 30%. I called my cardiologist to inquire about this and he prescribed a brand new Rx that was just approved in March 2020. So if you do take red yeast rice for cholesterol, you’re essentially taking an unregulated and potentially contaminated statin that wasn’t legal to sell in the first place! Hydrophilic statins such as rosuvastatin, fluvastatin, and there are instances in they. Improvement in cholesterol reverts back to baseline when this happens no life-extending effect like the statins JUPITER was far perfect! Side effects we need your help to protect themselves and their families, or it can be for. There ’ s most commonly prescribed drugs their high cholesterol with red yeast rice have. 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