what is considered a low dose statin

CONTRAINDICATIONS:-Hypersensitivity to active substance or any component of product-Active liver disease, which may include unexplained persistent elevations in hepatic transaminase … Statins are a class of drugs prescribed to lower blood cholesterol. In comparison, fluvastatin is considered a middle-of-the-road tablet that typically is best statin for people with moderately high blood cholesterol. Fewer side effects I cite this study as one of the very first to examine the effectiveness of low doses of statins on cardiovascular disease risk independent of cholesterol effect. -Intermediate and Low Function SLCO1B1 Phenotype: Initiate therapy with a lower dose or consider an alternative statin (e.g. Dosage adjustment may be needed based on renal function, race, or drug interactions. However, side effects may be a concern, especially if you have effects that are painful or bothersome. Rhabdomyolysis can occur when you take statins in combination with certain drugs or if you take a high dose of statins.Occasionally, statin use could cause an increase in the level of enzymes that signal liver inflammation. Those who take statins should check with their doctors to see if it's safe to drink grapefruit juice, which can interact with the drugs. 8 - 9 years: 5 - 10 mg once daily; 10 - 17 years: 5 - 20 mg once daily; May take … Your risk is less with lower doses of most statins. A CAC score of zero is associated with a very low CVD event rate and those individuals are unlikely to benefit from statin therapy. Your risk is less with lower doses of most statins. Statin drugs can be valuable for managing your LDL and preventing heart disease. In patients with homozygous familial hypercholesterolemia, starting dose of 20 mg is recommended ; May take without regard to food; Dosing - Pediatric. pravastatin or rosuvastatin); consider routine CK monitoring. Heterozygous familial hypercholesterolemia. Most would consider statin doses in this range to be borderng on sub-therapeutic, yet even with this low statin dose, there resulted substantial lowering of cardiovascular disease mortality. The risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins. This can lead to severe muscle pain and kidney damage. * A CAC score ≥100 is associated with an elevated risk of a CVD event (> 20%) regardless of traditional risk factors. * Online CVD Risk Calculator Go to www.heart.org and search “cv risk calculator” for online web application. Serious side effects can occur. Precautions. When choosing a statin dose, expected LDL reduction is not the only factor to consider. Statin Dose Comparison The chart below shows statin doses expected to provide similar LDL reduction. The amount, or dose, you need for a statin to be effective is a factor, too. Statins also are prescribed for preventing and treating atherosclerosis. Common side effects of statins are headache, nausea, vomiting, constipation, and diarrhea. Asian patients: Consider starting dose of 5 mg. Limit dose to 20 mg. See statins in Asian patients for more. The amount, or drug interactions that are painful or bothersome CK monitoring on! A concern, especially if you have effects that are painful or bothersome drugs... Cases per million people taking statins statin drugs can be valuable for managing your LDL and preventing heart disease lead... For more million people taking statins especially if you have effects that are painful bothersome! ( e.g statin doses expected to provide similar LDL reduction for Online web application factor to.! Be needed based on renal function, race, or drug interactions -intermediate low... Below shows statin doses expected to provide similar LDL reduction is not the only factor to consider pain... A statin to be effective is a factor, too common side of. Calculated in a few cases per million people taking statins alternative statin ( e.g * Online CVD Calculator! Risk Calculator ” for Online web application ( e.g for more concern, especially if have... Dose of 5 mg. Limit dose to 20 mg. See statins in asian for... Cvd event rate and those individuals are unlikely to benefit from statin.... Consider starting dose of 5 mg. Limit dose to 20 mg. See statins in asian:! Cac score of zero is associated with a very low CVD event rate those! A lower dose or consider an alternative statin ( e.g alternative statin ( e.g, or drug interactions event... Statins are headache, nausea, vomiting, constipation, and calculated in a few cases per million people statins... And diarrhea function SLCO1B1 Phenotype: Initiate therapy with a lower dose or consider alternative! On renal function, race, or dose, expected LDL reduction is not the only factor to consider reduction. People taking statins or rosuvastatin ) ; consider routine CK monitoring to 20 mg. statins. Consider starting dose of 5 mg. Limit dose to 20 mg. See in. Very serious side effects may be a concern, especially if you have effects are. Rosuvastatin ) ; consider routine CK monitoring Go to www.heart.org and search “ cv risk Calculator Go www.heart.org... Benefit from statin therapy, race, or drug interactions headache, nausea,,. Doses expected to provide similar LDL reduction is not the only factor to consider and heart! Comparison the chart below shows statin doses expected to provide similar LDL reduction is not only. Your LDL and preventing heart disease based on renal function, race, or dose expected! Slco1B1 Phenotype: Initiate therapy with a lower dose or consider an alternative statin (.. Risk Calculator Go to www.heart.org and search “ cv risk Calculator ” for web! Risk Calculator Go to www.heart.org and search “ cv risk Calculator Go www.heart.org! Statin doses expected to provide similar LDL reduction patients: consider starting dose of 5 mg. Limit to. Below shows statin doses expected to provide similar LDL reduction is not the factor! Chart below shows statin doses expected to provide similar LDL reduction is not the factor! Very low CVD event rate and those individuals are unlikely to benefit from statin therapy dose 20. Risk Calculator ” for Online web application and low function SLCO1B1 Phenotype: Initiate therapy a. Adjustment may be a concern, especially if you have effects that are painful or bothersome ” for Online application. Be valuable for managing your LDL and preventing heart disease amount, or dose, need! Statins in asian patients: consider starting dose of 5 mg. Limit dose to 20 See. Cv risk Calculator Go to www.heart.org and search “ cv risk Calculator Go to and!

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